{"id":17866,"date":"2011-11-12T05:34:30","date_gmt":"2011-11-12T05:34:30","guid":{"rendered":"http:\/\/www.mixedracestudies.org\/wordpress\/?p=17866"},"modified":"2011-11-13T18:46:28","modified_gmt":"2011-11-13T18:46:28","slug":"between-black-and-miscegenated-population-groups-sickle-cell-anemia-and-sickle-cell-trait-in-brazil-in-the-1930s-and-1940s","status":"publish","type":"post","link":"https:\/\/mixedracestudies.org\/wp\/?p=17866","title":{"rendered":"Between black and miscegenated population groups: sickle cell anemia and sickle cell trait in Brazil in the 1930s and 1940s"},"content":{"rendered":"

Between black and miscegenated population groups: sickle cell anemia and sickle cell trait in Brazil in the 1930s and 1940s<\/a><\/em><\/strong><\/p>\n

Hist\u00f3ria, Ci\u00eancias, Sa\u00fade-Manguinhos<\/a>
\nVolume 18, Number 2 (April\/June 2011)
\n29 pages
\nDOI: 10.1590\/S0104-59702011000200007<\/a><\/p>\n

Juliana Manzoni Cavalcanti<\/strong>, PhD candidate
\nGraduate Program on History of the Sciences and Health
\nCasa de Oswaldo Cruz\/Funda\u00e7\u00e3o Oswaldo Cruz<\/em><\/p>\n

Marcos Chor Maio<\/strong>, Senior Researcher and Professor
\nGraduate Program on History of the Sciences and Health
\nFiocruz \u2013 Casa de Oswaldo Cruz<\/em><\/p>\n

Translated by Diane Grosklaus Whitty<\/strong><\/p>\n

The article examines medical and scientific studies of sickle cell anemia<\/a> published in Brazil in the 1930s and 1940s<\/a>, when the vast majority of physicians and scientists believed that miscegenation<\/a> played a significant role in the epidemiology of the disease in the country. Special focus is placed on hematologist Ernani Martins da Silva, of the Oswaldo Cruz Institute, who conducted blood analyses around the interior of Brazil with the purpose of classifying miscegenated and allegedly pure population groups based on the presence of sickle cells and the racial distribution of blood groups. The article explores the ambivalences stemming from associations between sickle cell anemia and the ‘black race’ during this period.<\/p>\n

The term sickle cell disease (SCD) is applied to disorders caused by a specific change in the hemoglobin molecule, an oxygen-carrying molecule that is one of the most abundant within red blood cells. Genetic alteration causes one amino acid to be replaced with another in the protein chains that make up hemoglobin (with \u00df6 glutamic acid replaced by valine \u2013 Hb S), thereby altering the molecule\u2019s structure. This change lowers the affinity between the oxygen molecule and hemoglobin, prompting the formation of long hemoglobin chains that clump into intracellular bundles concentrated at the ends of the red blood cell and thus distort the cell into the crescent shape from which it gains its name (Andreoli et al., 1997, p.371)…<\/p><\/blockquote>\n

Read the entire article here<\/a>.<\/p>\n","protected":false},"excerpt":{"rendered":"

Between black and miscegenated population groups: sickle cell anemia and sickle cell trait in Brazil in the 1930s and 1940s Hist\u00f3ria, Ci\u00eancias, Sa\u00fade-Manguinhos Volume 18, Number 2 (April\/June 2011) 29 pages DOI: 10.1590\/S0104-59702011000200007 Juliana Manzoni Cavalcanti, PhD candidate Graduate Program on History of the Sciences and Health Casa de Oswaldo Cruz\/Funda\u00e7\u00e3o Oswaldo Cruz Marcos Chor […]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[12,83,21,2039,8],"tags":[8227,8225,8226,8233,8218,8221,8220,8219,8223,8222,8224,8235,8234],"class_list":["post-17866","post","type-post","status-publish","format-standard","hentry","category-articles","category-brazil","category-latincarib","category-health-medicine","category-media-archive","tag-diane-g-whitty","tag-diane-grosklaus-whitty","tag-diane-whitty","tag-ernani-martins-da-silva","tag-historia-ciencias-saude-manguinhos","tag-juliana-cavalcanti","tag-juliana-m-cavalcanti","tag-juliana-manzoni-cavalcanti","tag-marcos-c-maio","tag-marcos-chor-maio","tag-marcos-maio","tag-sickle-cell-anemia","tag-sickle-cell-disease"],"_links":{"self":[{"href":"https:\/\/mixedracestudies.org\/wp\/index.php?rest_route=\/wp\/v2\/posts\/17866","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/mixedracestudies.org\/wp\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/mixedracestudies.org\/wp\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/mixedracestudies.org\/wp\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/mixedracestudies.org\/wp\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=17866"}],"version-history":[{"count":0,"href":"https:\/\/mixedracestudies.org\/wp\/index.php?rest_route=\/wp\/v2\/posts\/17866\/revisions"}],"wp:attachment":[{"href":"https:\/\/mixedracestudies.org\/wp\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=17866"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/mixedracestudies.org\/wp\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=17866"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/mixedracestudies.org\/wp\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=17866"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}