{"id":4140,"date":"2009-12-30T01:18:14","date_gmt":"2009-12-30T01:18:14","guid":{"rendered":"http:\/\/www.mixedracestudies.org\/wordpress\/?p=4140"},"modified":"2012-03-14T00:51:43","modified_gmt":"2012-03-14T00:51:43","slug":"pre-hispanic-mesoamerican-demography-approximates-the-present-day-ancestry-of-mestizos-throughout-the-territory-of-mexico","status":"publish","type":"post","link":"https:\/\/mixedracestudies.org\/wp\/?p=4140","title":{"rendered":"Pre-Hispanic Mesoamerican demography approximates the present-day ancestry of Mestizos throughout the territory of Mexico"},"content":{"rendered":"

Pre-Hispanic Mesoamerican demography approximates the present-day ancestry of Mestizos throughout the territory of Mexico<\/a><\/em><\/strong><\/p>\n

American Journal of Physical Anthropology<\/a>
\nVolume 139 Issue 3
\nPages 284 – 294
\nPublished Online: 2009-01-12<\/p>\n

Rodrigo Rubi-Castellanos
\n<\/strong>Instituto de Investigaci\u00f3n en Gen\u00e9tica Molecular, Centro Universitario de la Ci\u00e9nega, (CUCi\u00e9nega-UdeG), Ocotl\u00e1n, Jalisco, M\u00e9xico<\/em><\/p>\n

Gabriela Mart\u00ednez-Cort\u00e9s<\/strong>
\nInstituto de Investigaci\u00f3n en Gen\u00e9tica Molecular, Centro Universitario de la Ci\u00e9nega, (CUCi\u00e9nega-UdeG), Ocotl\u00e1n, Jalisco, M\u00e9xico<\/em><\/p>\n

Jos\u00e9 Francisco Mu\u00f1oz-Valle<\/strong>
\nInstituto de Investigaci\u00f3n en Reumatolog\u00eda y del Sistema M\u00fasculo-Esquel\u00e9tico, Centro Universitario de Ciencias de la Salud (CUCS-UdeG), Guadalajara, Jalisco, M\u00e9xico<\/em><\/p>\n

Antonio Gonz\u00e1lez-Mart\u00edn<\/strong>
\nDepartamento de Zoolog\u00eda y Antropolog\u00eda F\u00edsica, Universidad Complutense de Madrid (UCM), 28040 Madrid, Spain<\/em><\/p>\n

Ricardo M. Cerda-Flores<\/strong>
\nDepartamento de Gen\u00e9tica de Poblaciones y Bioinform\u00e1tica, Centro de Investigaci\u00f3n Biom\u00e9dica del Noreste (CIBN-IMSS), Monterrey, Nuevo Le\u00f3n, M\u00e9xico<\/em><\/p>\n

Manuel Anaya-Palafox<\/strong>
\nLaboratorio de Gen\u00e9tica Forense, Instituto Jalisciense de Ciencias Forenses (IJCF), Tlaquepaque, Jalisco, M\u00e9xico<\/em><\/p>\n

H\u00e9ctor Rangel-Villalobos<\/a><\/strong>
\nInstituto de Investigaci\u00f3n en Gen\u00e9tica Molecular, Centro Universitario de la Ci\u00e9nega, (CUCi\u00e9nega-UdeG), Ocotl\u00e1n, Jalisco, M\u00e9xico<\/p>\n

Rodrigo Rubi-Castellanos<\/strong> and H\u00e9ctor Rangel-Villalobos<\/strong> contributed equally to this work.<\/p>\n

Over the last 500 years, admixture among Amerindians<\/a>, Europeans, and Africans, principally, has come to shape the present-day gene pool of Mexicans, particularly Mestizos<\/a>, who represent about 93% of the total Mexican population. In this work, we analyze the genetic data of 13 combined DNA<\/a> index system-short tandem repeats (CODIS<\/a>-STRs) in 1,984 unrelated Mestizos representing 10 population samples from different regions of Mexico<\/a>, namely North, West, Central, and Southeast. The analysis of molecular variance (AMOVA)<\/a> test demonstrated low but significant differentiation among Mestizos from different regions (FST<\/sub><\/a> = 0.34%; P<\/a> = 0.0000). Although the spatial analysis of molecular variance (SAMOVA) predicted clustering Mestizo populations into four well-delimited groups, the main differentiation was observed between Northwest when compared with Central and Southeast regions. In addition, we included analysis of individuals of Amerindian (Purepechas<\/a>), European (Huelva, Spain<\/a>), and African (Fang<\/a>) origin. Thus, STRUCTURE analysis was performed identifying three well-differentiated ancestral populations (k = 3). STRUCTURE results and admixture estimations by means of LEADMIX software in Mestizo populations demonstrated genetic heterogeneity or asymmetric admixture throughout Mexico, displaying an increasing North-to-South gradient of Amerindian ancestry, and vice versa regarding the European component. Interestingly, this distribution of Amerindian ancestry roughly reflects pre-Hispanic Native-population density, particularly toward the Mesoamerican<\/a> area. The forensic, epidemiological, and evolutionary implications of these findings are discussed herein.<\/p>\n","protected":false},"excerpt":{"rendered":"

Pre-Hispanic Mesoamerican demography approximates the present-day ancestry of Mestizos throughout the territory of Mexico American Journal of Physical Anthropology Volume 139 Issue 3 Pages 284 – 294 Published Online: 2009-01-12 Rodrigo Rubi-Castellanos Instituto de Investigaci\u00f3n en Gen\u00e9tica Molecular, Centro Universitario de la Ci\u00e9nega, (CUCi\u00e9nega-UdeG), Ocotl\u00e1n, Jalisco, M\u00e9xico Gabriela Mart\u00ednez-Cort\u00e9s Instituto de Investigaci\u00f3n en Gen\u00e9tica Molecular, […]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1649,12,21,8,103],"tags":[4633,2343,1651,1655,1653,1658,1654,1657,20753,1656,1652],"class_list":["post-4140","post","type-post","status-publish","format-standard","hentry","category-anthropology","category-articles","category-latincarib","category-media-archive","category-mexico","tag-afro-mexicans","tag-afromexicans","tag-american-journal-of-physical-anthropology","tag-antonio-gonzalez-martin","tag-gabriela-martinez-cortes","tag-hector-rangel-villalobos","tag-jose-francisco-munoz-valle","tag-manuel-anaya-palafox","tag-mexico","tag-ricardo-m-cerda-flores","tag-rodrigo-rubi-castellanos"],"_links":{"self":[{"href":"https:\/\/mixedracestudies.org\/wp\/index.php?rest_route=\/wp\/v2\/posts\/4140","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/mixedracestudies.org\/wp\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/mixedracestudies.org\/wp\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/mixedracestudies.org\/wp\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/mixedracestudies.org\/wp\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=4140"}],"version-history":[{"count":0,"href":"https:\/\/mixedracestudies.org\/wp\/index.php?rest_route=\/wp\/v2\/posts\/4140\/revisions"}],"wp:attachment":[{"href":"https:\/\/mixedracestudies.org\/wp\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=4140"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/mixedracestudies.org\/wp\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=4140"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/mixedracestudies.org\/wp\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=4140"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}