{"id":63589,"date":"2022-03-29T19:19:43","date_gmt":"2022-03-29T19:19:43","guid":{"rendered":"http:\/\/www.mixedracestudies.org\/?p=63589"},"modified":"2022-03-29T20:32:14","modified_gmt":"2022-03-29T20:32:14","slug":"genetic-ancestry-in-precision-medicine-is-reshaping-the-race-debate","status":"publish","type":"post","link":"https:\/\/mixedracestudies.org\/wp\/?p=63589","title":{"rendered":"Genetic ancestry in precision medicine is reshaping the race debate"},"content":{"rendered":"<p><a href=\"https:\/\/doi.org\/10.1073\/pnas.2203033119\" target=\"_blank\" rel=\"noopener\"><em><strong>Genetic ancestry in precision medicine is reshaping the race debate<\/strong><\/em><\/a><\/p>\n<p><a href=\"https:\/\/www.pnas.org\/\" target=\"_blank\" rel=\"noopener\">Proceedings of the National Academy of Sciences<\/a><br \/>\n<a href=\"https:\/\/www.pnas.org\/toc\/pnas\/119\/12\" target=\"_blank\" rel=\"noopener\">Volume 119, Number 12<\/a>, Article <a href=\"https:\/\/www.pnas.org\/doi\/10.1073\/pnas.2203033119\" target=\"_blank\" rel=\"noopener\">e2203033119<\/a><br \/>\n4 pages<br \/>\n2022-03-16<br \/>\nDOI: <a href=\"https:\/\/doi.org\/10.1073\/pnas.2203033119\" target=\"_blank\" rel=\"noopener\">10.1073\/pnas.2203033119<\/a><\/p>\n<p><a href=\"mailto:tkrainc@alumni.princeton.edu\" target=\"_blank\" rel=\"noopener\"><strong>Talia Krainc<\/strong><\/a><br \/>\nDepartment of Anthropology<br \/>\n<em>Princeton University, Princeton, New Jersey<\/em><\/p>\n<p><a href=\"https:\/\/twitter.com\/Anthrofuentes\" target=\"_blank\" rel=\"noopener\"><strong>Agust\u00edn Fuentes<\/strong><\/a>, Professor of Anthropology<br \/>\n<em>Princeton University, Princeton, New Jersey<\/em><\/p>\n<figure><a href=\"https:\/\/doi.org\/10.1073\/pnas.2203033119\" target=\"_blank\" rel=\"noopener\"><img decoding=\"async\" style=\"width: 67%; display: block; margin-left: auto; margin-right: auto;\" src=\"https:\/\/www.pnas.org\/cms\/10.1073\/pnas.2203033119\/asset\/0c6b3784-a3d0-4cb8-aff4-6f59cb499bdf\/assets\/images\/large\/pnas.2203033119fig01.jpg\"><\/a><figcaption style=\"font-size: x-small; width: 67%; display: block; margin-left: auto; margin-right: auto;\">When including more diverse populations and ancestries in genetic and clinical studies, we need to avoid conflating race with biological identity. <em>Image credit: Shutterstock\/tai11.<\/em><\/figcaption><\/figure>\n<p><a href=\"https:\/\/en.wikipedia.org\/wiki\/Precision_medicine\" target=\"_blank\" rel=\"noopener\">Precision medicine<\/a> is an emerging field with immense potential for better understanding of diseases and improved treatment outcomes (<a href=\"https:\/\/www.pnas.org\/doi\/10.1073\/pnas.2203033119#core-r1\" target=\"_blank\" rel=\"noopener\">1<\/a>). Its focus: patterns of <a href=\"https:\/\/en.wikipedia.org\/wiki\/Human_genetic_variation\" target=\"_blank\" rel=\"noopener\">human genetic variation<\/a> in populations and individuals\u2014and how such patterns influence disease pathology and treatment. The field rejects the \u201cone size fits all\u201d approach to understanding disease, aspiring to develop tailored therapies that optimize treatment efficacy. It\u2019s a promising but fledgling field that faces numerous challenges, both scientific and practical. But one challenge has not been fully appreciated: the lack of genetic diversity in research and clinical studies (<a href=\"https:\/\/www.pnas.org\/doi\/10.1073\/pnas.2203033119#core-r2\" target=\"_blank\" rel=\"noopener\">2<\/a>, <a href=\"https:\/\/www.pnas.org\/doi\/10.1073\/pnas.2203033119#core-r3\" target=\"_blank\" rel=\"noopener\">3<\/a>)&#8230;<\/p>\n<p>Read the entire article <a href=\"https:\/\/doi.org\/10.1073\/pnas.2203033119\" target=\"_blank\" rel=\"noopener\">here<\/a>.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>The field rejects the \u201cone size fits all\u201d approach to understanding disease, aspiring to develop tailored therapies that optimize treatment efficacy. It\u2019s a promising but fledgling field that faces numerous challenges, both scientific and practical.<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[12,2039,8],"tags":[17326,738,737,33352],"class_list":["post-63589","post","type-post","status-publish","format-standard","hentry","category-articles","category-health-medicine","category-media-archive","tag-agustin-fuentes","tag-pnas","tag-proceedings-of-the-national-academy-of-sciences","tag-talia-krainc"],"_links":{"self":[{"href":"https:\/\/mixedracestudies.org\/wp\/index.php?rest_route=\/wp\/v2\/posts\/63589","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/mixedracestudies.org\/wp\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/mixedracestudies.org\/wp\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/mixedracestudies.org\/wp\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/mixedracestudies.org\/wp\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=63589"}],"version-history":[{"count":2,"href":"https:\/\/mixedracestudies.org\/wp\/index.php?rest_route=\/wp\/v2\/posts\/63589\/revisions"}],"predecessor-version":[{"id":63599,"href":"https:\/\/mixedracestudies.org\/wp\/index.php?rest_route=\/wp\/v2\/posts\/63589\/revisions\/63599"}],"wp:attachment":[{"href":"https:\/\/mixedracestudies.org\/wp\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=63589"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/mixedracestudies.org\/wp\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=63589"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/mixedracestudies.org\/wp\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=63589"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}