{"id":7943,"date":"2010-07-09T21:57:27","date_gmt":"2010-07-09T21:57:27","guid":{"rendered":"http:\/\/www.mixedracestudies.org\/wordpress\/?p=7943"},"modified":"2010-07-10T01:06:33","modified_gmt":"2010-07-10T01:06:33","slug":"genetic-ancestry-data-improve-diagnosis-in-asthma-and-lung-disease","status":"publish","type":"post","link":"https:\/\/mixedracestudies.org\/wp\/?p=7943","title":{"rendered":"Genetic ancestry data improve diagnosis in asthma and lung disease"},"content":{"rendered":"

Genetic ancestry data improve diagnosis in asthma and lung disease<\/a><\/em><\/strong><\/p>\n

University of California, San Fransisco
\nNews Release
\n2010-07-07<\/p>\n

Kristen Bole<\/a><\/strong><\/p>\n

Released Jointly by UCSF and Northwestern University Feinberg School of Medicine, Henry Ford Hospital, and National Jewish Health<\/em><\/p>\n

Americans with lung disease may face a far greater level of lung damage than either they or their doctor suspect, depending on their individual genetic heritage, according to a study released July 7<\/a>. The research implications range from diagnosing the severity of asthma to disability decisions or eligibility for lung transplants, researchers say.<\/p>\n

In the largest study of its kind to date, spanning a dozen research centers and pooling data on more than 3,000 patients, a team of researchers led by UCSF and Northwestern University found that patients\u2019 precise genetic background told far more about their potential lung function \u2013 and therefore any damage that has occurred \u2013 than the self-identified racial profile commonly used in such tests.<\/p>\n

The results point to a more precise method of assessing patients\u2019 lung function, as well as the potential impact of using precise genetic benchmarks for assessing health overall, researchers say. Findings will appear in the July 22 print edition of the \u201cNew England Journal of Medicine\u201d and online on July 7 at nejm.org<\/a>.<\/p>\n

…Standard race categories, however, don\u2019t capture the extent of our ancestral diversity, according to the paper\u2019s senior author, Esteban G. Burchard<\/a>, MD, MPH, who is director of the UCSF Center for Genes, Environment and Health, and a member of the Department of Bioengineering and Therapeutic Sciences, a joint department between the UCSF schools of Medicine and Pharmacy.<\/p>\n

\u201cPeople throughout the world have a richer genetic heritage than can be captured by our current definitions of race,\u201d <\/strong>Burchard said, noting that almost every continent has large populations that are known to be genetically mixed. \u201cWhen we force patients into an individual box, such as \u2018African-American\u2019 or \u2018Caucasian\u2019, we\u2019re missing a lot of genetic information.\u201d<\/strong><\/p>\n

While this study focused on patients who define themselves as African-Americans, the participants\u2019 actual genetic ancestry ranged broadly and included Caucasian and African heritage<\/strong>…<\/p>\n

To read the entire article, click here<\/a>.<\/p>\n","protected":false},"excerpt":{"rendered":"

Genetic ancestry data improve diagnosis in asthma and lung disease University of California, San Fransisco News Release 2010-07-07 Kristen Bole Released Jointly by UCSF and Northwestern University Feinberg School of Medicine, Henry Ford Hospital, and National Jewish Health Americans with lung disease may face a far greater level of lung damage than either they or […]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[12,2039,6,20],"tags":[3263,3261,3262,3260,3259,3258,3264],"class_list":["post-7943","post","type-post","status-publish","format-standard","hentry","category-articles","category-health-medicine","category-new-media","category-usa","tag-esteban-burchard","tag-esteban-g-burchard","tag-esteban-gonzalez-burchard","tag-kristen-bole","tag-san-fransisco","tag-university-of-california","tag-university-of-california-at-san-fransisco"],"_links":{"self":[{"href":"https:\/\/mixedracestudies.org\/wp\/index.php?rest_route=\/wp\/v2\/posts\/7943","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/mixedracestudies.org\/wp\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/mixedracestudies.org\/wp\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/mixedracestudies.org\/wp\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/mixedracestudies.org\/wp\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=7943"}],"version-history":[{"count":0,"href":"https:\/\/mixedracestudies.org\/wp\/index.php?rest_route=\/wp\/v2\/posts\/7943\/revisions"}],"wp:attachment":[{"href":"https:\/\/mixedracestudies.org\/wp\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=7943"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/mixedracestudies.org\/wp\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=7943"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/mixedracestudies.org\/wp\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=7943"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}