Heterogeneity of risk within racial groups, a challenge for public health programs

Posted in Articles, Health/Medicine/Genetics, Media Archive, United States on 2012-11-11 00:53Z by Steven

Heterogeneity of risk within racial groups, a challenge for public health programs

Preventive Medicine
Volume 55, Issue 5, November 2012
Pages 405–408
DOI: 10.1016/j.ypmed.2012.08.022

Sean A. Valles, Assistant Professor
Lyman Briggs College, Michigan State University

Targeting high-risk populations for public health interventions is a classic tool of public health promotion programs. This practice becomes thornier when racial groups are identified as the at-risk populations. I present the particular ethical and epistemic challenges that arise when there are low-risk subpopulations within racial groups that have been identified as high-risk for a particular health concern. I focus on two examples. The black immigrant population does not have the same hypertension risk as US-born African Americans. Similarly, Finnish descendants have a far lower rate of cystic fibrosis than other Caucasians. In both cases the exceptional nature of these subpopulations has been largely ignored by the designers of important public health efforts, including the recent US government dietary recommendations. I argue that amending the publicly-disseminated risk information to acknowledge these exceptions would be desirable for several reasons. First, recognizing low-risk subpopulations would allow more efficient use of limited resources. Communicating this valuable information to the subpopulations would also promote truth-telling. Finally, presenting a more nuanced empirically-supported representation of which groups are at known risk of diseases (not focusing on mere racial categories) would combat harmful biological race essentialist views held by the public.

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Race Under the Microscope: Biological Misunderstandings of Race

Posted in Health/Medicine/Genetics, Media Archive, Politics/Public Policy, Social Science, Videos on 2012-11-10 23:00Z by Steven

Race Under the Microscope: Biological Misunderstandings of Race

Center for Genetics and Society
2012-05-24

Despite the fact that advances in genetics undermine the notion that discrete and distinct racial groups exist at the biological level, the science of genetics is inadvertently reinforcing the myth that race is a biological, rather than a social, category. In this video, produced by the Center for Genetics and Society, a group of experts discusses the history and consequences of the misuse of racial categories in medicine and science. The video is a great resource for students and educators.

Race Under the Microscope features commentary on the misuse of race from esteemed professors Jonathan Kahn (Professor of Law, Hamline University), Dorothy Roberts (Professor of Law, Northwestern University), Osagie K. Obasogie (Professor of Law, University of California Hastings Law School), and Joseph Graves (Associate Dean for Research, Joint School for Nanosciences & Nanoengineering, Greensboro, NC). The excerpts used in the video were filmed during the 2011 Tarrytown Meeting.

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Heredity in Color

Posted in Articles, Health/Medicine/Genetics, Media Archive, Oceania on 2012-11-09 05:08Z by Steven

Heredity in Color

Hawke’s Bay Herald
New Zealand
Volume XXIII, Issue 7956
1888-01-21
Page 2
Source: Papers Past, National Library of New Zealand Te Puna Mātauranga o Aotearoa

If a white man marries a negro, their children, boys and girls alike, are all mulattos. Lot us make to ourselves no allusions or mistakes upon this score—each one is simply and solely a pure mulatto, exactly half-way in color, feature, hair, and statue, between his father’s face and his mother’s. People who have not lived in a mixed community of blacks and whites often ignore or misunderstand this fundamental fact of hereditary philosophy; they imagine that one of the children of such a marriage may be light brown, and another dark brown; one almost white, and one almost black; that the resulting strains may to a great extent be mingled indefinitely and in varying proportions. Not a bit of it. A mulatto is a mulatto, and a quadroon is a quadroon, with just one-half and one-fourth of negro blood respectively; and anyone who has once lived in an ox-slave-owning country can pick out the proportion of black or white elements in any particular brown person he meets with as much accuracy as the stud-book shows in recording the pedigree of famous racehorses. Black and white produce mulattos — all mulattos alike to a shade of identity; mulatto and white produce quadroon, and no mistake about it; mulatto and black produce sambo; quadroon and white octoroon—and so forth ad infinitum. After the third cross persistently in either direction, the strain of which less than one-eighth persists becomes at last practically indistinguishable, and the child is ” white by law ” or ” black by law,” as the case may be, without the faintest mark of its slight opposite intermixture. I speak hero of facts which I have carefully examined at firsthand; all the nonsensical talk about finger-nails and knuckles, and persistence of the negro type for ever, is pure unmitigated slave-owning prejudice. The child of an octoroon by a white man is simply white; and no acuteness on earth, no scrutiny conceivable would ever discover the one-sixteenth share of black blood by any possible test save documentary evidence. Here, then, we have a clear, physical, and almost mathematically demonstrable case, showing that, so far as regards bodily peculiarities at least, the child is on the average just equally compounded of traits derived from both its parents. Among hundreds and hundreds of mulatto and quadroon children whom I have observed, I have never known a single genuine instance to the contrary. Heredity comes out exactly true; you get just as much of each color in every case as you would naturally expect to do from a mixture of given proportions. In other words, all mulattos are recognisably different from all quadroons, and all quadroons from all octoroons or all sambos.—From “The Cause of Character,” in the Cornhill Magazine.

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Regular screening mammography before the diagnosis of breast cancer reduces black:white breast cancer differences and modifies negative biological prognostic factors

Posted in Articles, Health/Medicine/Genetics, Media Archive, United States, Women on 2012-11-03 01:35Z by Steven

Regular screening mammography before the diagnosis of breast cancer reduces black:white breast cancer differences and modifies negative biological prognostic factors

Breast Cancer Research and Treatment
Volume 135, Number 2 (2012)
pages 549-553
DOI: 10.1007/s10549-012-2193-3

Paula Grabler
Feinberg College of Medicine
Northwestern University

Danielle Dupuy
Metropolitan Chicago Breast Cancer Taskforce, Chicago, Illinois

Jennifer Rai
University of Michigan College of Medicine

Sean Bernstein
Rush University Medical Center, Chicago, Illinois

David Ansell
Rush University Medical Center, Chicago, Illinois

Black women present with later stage breast cancers compared to white women, and their cancers are more likely to be larger, receptor negative, and undifferentiated. This study evaluated black:white differences in the stage and biology of breast cancer among women who had a screening mammogram at one of two Chicago academic medical centers within two years of the breast cancer diagnosis (regularly screened) and compared them to the black:white differences in the stage and biology of breast cancer in women who had not received mammographic screening within two years of a breast cancer diagnosis (irregularly screened.) There were no significant black:white differences in the proportion of early breast cancers (black = 74 %; white = 69 %, p = NS) in the regularly screened population or in the irregularly screened group (black = 60 %; white = 68 %, p = NS.) The regularly screened population received significantly more mammograms (58 % ≥4 mammograms) compared to the irregularly screened population (41 % ≥4 mammograms.) Black women in the regularly screened population were less likely than irregularly screened black women to have estrogen negative breast cancers (26 vs. 36 %, p < .05), progesterone negative breast cancers (35 vs. 46 %, p < .05), and poorly differentiated breast cancers (39 vs. 53 %, p < .05.) White women in the irregularly screened population also had worse prognostic factors than white women in the regularly screened population, though these were not statistically significant. Regular mammographic screening can contribute to the narrowing of black:white differences in presentation of breast cancer.

Read or purchase the article here.

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Race in a Bottle

Posted in Articles, Health/Medicine/Genetics, Media Archive, Politics/Public Policy, United States on 2012-10-29 17:35Z by Steven

Race in a Bottle

Scientific American
Volume 297 (January 1, 2007)
pages 40-45

Jonathan D. Kahn, Professor of Law
Hamline University, Saint Paul, Minnesota

Drugmakers are eager to develop medicines targeted at ethnic groups, but so far they have made poor choices based on unsound science. This article focuses on the drug, BiDil – a drug that combats congestive heart failure by dilating the arteries and veins of African American patients. The author expounds that there is no solid evidence that the drug should targeted towards only one ethnic group. The author includes the history of BiDil including its inception and then its reappearance with a race-based focus.

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Spirometry, Measurement, and Race in the Nineteenth Century

Posted in Articles, Health/Medicine/Genetics, History, Media Archive on 2012-10-27 21:43Z by Steven

Spirometry, Measurement, and Race in the Nineteenth Century

Journal of the History of Medicine and Allied Sciences
Volume 60, Number 2, April 2005
pages 135-169

Lundy Braun, Royce Family Professor in Teaching Excellence and Professor of Medical Science and Africana Studies
Brown University

Race correction is a common practice in contemporary pulmonary medicine that involves mathematical adjustment of lung capacity measurements in populations designated as “black” using standards derived largely from populations designated as “white.” This article traces the history of the racialization and gendering of spirometry through an examination of the ideas and practices related to lung capacity measurements that circulated between Britain and the United States in the nineteenth century. Lung capacity was first conceptualized as a discrete entity of potential use in the diagnosis of pulmonary disease and monitoring of the vitality of the armed forces and other public servants in spirometric studies conducted in mid-nineteenth-century Britain. The spirometer was then imported to the United States and used to measure the capacity of the lungs in a large study of black and white soldiers in the Union Army sponsored by the U.S. Sanitary Commission at the end of the Civil War. Despite contrary findings and contestation by leading black intellectuals, the notion of mean differences between racial groups in the capacity of the lungs became deeply entrenched in the popular and scientific imagination in the nineteenth century, leaving unexamined both the racial categories deployed to organize data and the conditions of life that shape lung function.

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Ocular Anthropomorphisms: Eugenics and Primatology at the Threshold of the “Almost Human”

Posted in Articles, Health/Medicine/Genetics, History, Live Events, Philosophy, Social Science, United States on 2012-10-24 01:44Z by Steven

Ocular Anthropomorphisms: Eugenics and Primatology at the Threshold of the “Almost Human”

Social Text
Volume 30, Number 3 112
pages 97-121
DOI: 10.1215/01642472-1597350

Megan H. Glick, Assistant Professor of Women’s and Gender Studies and Africana Studies
Dickinson College, Carlisle, Pennsylvania

From the moment Charles Darwin proposed Africa as the site of human origins, scientists and the lay public alike labored to reconcile contemporary racial hierarchies with the possibility of a universal African birthplace. Previous historical treatments of this phenomenon have focused on the search for the “missing link” in Asia and Europe, an investigation that, if successful, would have effectively established a separate ancestry for the white races. This essay identifies a new component of this history: the racialization of higher-order primates within the nascent discipline of primatology and within US popular culture between the 1910s and 1930s. Departing from Donna Haraway’s originary work on the field, this essay argues that primatology was in fact built upon preexisting scientific racial ideologies, such that the animals themselves became parsed according to racial categorizations. In particular, the anthropomorphization and “whitening” of the chimpanzee on the one hand, and the bestialization and “blackening” of the gorilla on the other, provided a forum for ideas about biological essentialism, evolutionary capabilities, and racial difference. This alternative history is revealed through an examination of the photographic archives and written work of longtime eugenicist and founding primatologist Robert Mearns Yerkes, and through a contextualization of these documents within contemporary scientific and popular cultures. By tracing the lineage of American primatology to the closing arc of eugenic science, this essay seeks to enrich and reimagine the relationship between practices of racialization and speciation within the larger histories of evolutionary thought and racial formation.

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The New Virginia Law To Preserve Racial Integrity

Posted in Articles, Health/Medicine/Genetics, Law, Media Archive, Politics/Public Policy, United States, Virginia on 2012-10-21 20:28Z by Steven

The New Virginia Law To Preserve Racial Integrity

Virginia Health Bulletin
Virginia Department of Health
Volume XVI, Extra Number 2 (March 1924)
pages 1-4
Source: Pamphlet: Rockbridge County Clerk’s Correspondence, 1912–1943. Local Government Records Collection. The Library of Virginia, (Racial Integrity Act Documents) 12-1245-005

W. A. Plecker, M. D.
State Registrar of Vital Statistics, Richmond, Virginia

Senate Bill 219, To preserve racial integrity, passed the House March 8, 1924, and is now a law of the State.

This bill aims at correcting a condition which only the more thoughtful people of Virginia know the existence of.

It is estimated that there are in the State from 10,000 to 20,000, possibly more, near white people, who are known to possess an intermixture of colored blood, in some cases to a slight extent it is true, but still enough to prevent them from being white.

In the past it has been possible for these people to declare themselves as white, or even to have the Court so declare them. Then they have demanded tho admittance of their children into the white schools, and in not a few cases have intermarried with white people.

In many counties they exist as distinct colonies holding themselves aloof from negroes, but not being admitted by the white people as of their race.

In any large gathering or school of colored people, especially in the cities, many will be observed who are scarcely distinguishable as colored.

These persons, however, are not white in reality, nor by the new definition of this law, that a white person is one with no trace of the blood of another race, except that a person with one-sixteenth of the American Indian, if there is no other race mixture, may be classed as white.

Their children are likely to revert to the distinctly negro type even when all apparent evidence of mixture has disappeared.

The Virginia Bureau of Vital Statistics has been called upon within one month for evidence by two lawyers employed to assist people of this type to force their children into the white public schools, and by another employed by the school trustees of a district to prevent this action.

In each case evidence was found to show that either the people themselves or their connect ions were reported to our office to be of mixed blood.

Our Bureau has kept a watchful eye upon the situation, and has guarded the welfare of the State as far as possible with inadequate law and power. The condition has gone on, however, and is rapidly increasing in importance.

Unless radical measures are used to prevent it, Virginia and other parts of the Nation must surely in time go the way of all other countries in which people of two or more races have lived in close contact. With the exception of the Hebrew race, complete intermixture or amalgamation has been the inevitable result.

To succeed, the intermarriage of the white race with mixed stock must be made impossible. But that is not sufficient, public sentiment must be so aroused that intermixture out of wedlock will cease.

The public must be led to look with scorn and contempt upon the man who will degrade himself and do harm to society by such abhorrent deeds.

The Bureau of Vital Statistics, Clerks who issue marriage licenses, and the school authorities are the barriers placed by this law between the danger and the safety of the Commonwealth…

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The Meaning of Race in the DNA Era: Science, History and the Law

Posted in Articles, Health/Medicine/Genetics, History, Law, Media Archive on 2012-10-18 21:29Z by Steven

The Meaning of Race in the DNA Era: Science, History and the Law

The Temple Journal of Science, Technology & Environmental Law
Volume 27, Number 2 (Fall 2008)
pages 231-265

Christian B. Sundquist, Associate Professor of Law
Albany Law School

INTRODUCTION

What is “race”? Does the concept of race represent a natural and inevitable understanding of human difference? Does race have any biological meaning, or is it merely an artificial construct employed by society and political bodies? If race is the former, then how can modern society avoid a rebirth of racial eugenics? And yet if race is an arbitrary tool of social organization without genetic content, then how should we interpret purported forensic racial determinations based on DNA analyses?

Race is biology. Race is ancestry. Race is genetic.

The meaning of “race” is constantly questioned yet rarely understood. Early theories of race assigned social, intellectual, and moral values to perceived differences among groups of people. The perception that race should be defined in terms of genetic and biologic difference fueled the “race science” of the eighteenth and nineteenth centuries, during which time geneticists, physiognomists, eugenicists, anthropologists and others purported to find scientific justification for denying equal treatment to non-“white” persons.

Part I of this article thus examines the provenance of the “race” concept. The categorization of humans into “racial” groups was neither natural nor inevitable. The initial separation of humans into “racial” categories was understood to simply reflect inherent biological differences between groups of people. These differences supposedly accounted for natural variances in intelligence, morality, and physical and sexual prowess. As such, these pseudo-biological differences were used to justify and explain power differentials between “races” of people.

Race is constructed. Race is biologically meaningless. Race is power.

The pseudo-scientific understandings of race supplied by nineteenth-century geneticists and biologists were applied by Nazi Germany in a manner that shocked the world. As a result, the concept of race following World War II increasingly was understood as a socio-political construction with no biological meaning. Modern sociological theories thus uniformly understand race as a social grouping of persons necessary to preserve unbalanced relationships of power. Part II of this article examines this post-war refutation of nineteenth-century “race science,” as well as the core assumptions underlying modern racial theory.

Race is phenotype. Race is color. Race is language. Race is citizenship. Race is class. Race is culture. Race is assimilation. Race is law.

Reducing race to a single critical “essence” is an impossible endeavor. While one’s phenotype and color may contribute to racial categorization, so can one’s national origin, social class and language. As a result, race has a complex social meaning that depends in part on the prevailing “common understanding and meaning” of society. Not-so-antiquated notions of race once deemed Italian, Irish and Southern European immigrants and their descendants as “non-white” and cursed with inferior genetic stock. These groups eventually obtained “Whiteness” based on changing social understandings of their assimilatory potential, and the formation of a racial identity defined in opposition to “Blackness.” The elusive nature of race is similarly illustrated by the conflict between the legal racialization of Middle Eastern and Mexican persons as “white” during certain historical periods, and the social racialization of these persons as “non-white” and racially distinct during other times.

Race is subjective. Race is objective. Race is whiteness. Race is blackness. Race is fixed. Race is malleable. Race is performance.

Race is constantly in flux depending on one’s baseline understanding of the nature of race. I am black according to certain understandings of race, while other interpretations may render me white. I am Latino, Creole, Egyptian, and “other” according to some outsider interpretations of race, yet I can also be reduced to “mixed” by utilizing an alternative understanding of race. Outsider perceptions of race in turn may change according to my performance of race, and how race is performed around me.
Race is biology.

Race is ancestry. Race is genetic.

Notwithstanding the post-war rejection of a biological interpretation of race, modern genetic science has increasingly claimed the ability to identify “race” through the biological analysis of DNA samples. Law enforcement agencies in the United States and elsewhere analyze individual DNA samples to identify the likely “race” of a criminal suspect, while courts in the United States increasingly admit expert testimony stating the statistical probability that a criminal suspect belongs to a specific race based on such DNA analyses. Such a re-biologicalization of race clearly contradicts the classical post-war theory of race as a social construct. Part III of this article examines the contemporary re-interpretation of race as having some biologically traceable genetic essence.

Race is constructed. Race is biologically meaningless. Race is power.

The claims of modern genetics notwithstanding, race remains a biologically meaningless concept of human categorization. Race simply has no traceable genetic essence, and the proliferation of racial DNA testing represents a fundamental misunderstanding of the nature of race rather than the neutral application of scientific principles. Part IV of this article argues that contemporary genetics has misapprehended the elusive nature of race in a manner strikingly similar to that of the nineteenth-century race science…

Read the entire article here.

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Review of Fatal Invention, by Professor Dorothy Roberts

Posted in Articles, Book/Video Reviews, Health/Medicine/Genetics, Media Archive, United States on 2012-10-18 18:00Z by Steven

Review of Fatal Invention, by Professor Dorothy Roberts

Race and the Law: A Critical Examination of Science, Law and the Construction of Race
2011-12-07

Christian B. Sundquist, Associate Professor of Law
Albany Law School

Professor Dorothy Roberts has recently released a vitally important book on issues of race and genetics, entitled Fatal Invention: How Science, Politics, and Big Business Re-Create Race in the Twenty-First Century (2011). Professor Roberts thoughtfully engages the modern legal and scientific preoccupation with genetic theories of race. Examining the “new racial science” in a variety of contexts, including pharmacology, biomedical research, immigration screening, criminal justice, ancestry testing, and genetic surveillance, Professor Roberts deconstructs the myth of intrinsic racial difference through a lively use of historical and scientific sources. While the entire book is a massive achievement in the burgeoning field of genetics and race, a few insights stand out as particularly compelling. First, Professor Roberts makes a convincing argument that it is problematic to label the racial science of yore “pseudoscience.” It is quite tempting to ridicule both the old and new forms of racial science as ignorant and biased attempts to valorize racial hierarchy. Professor Roberts notes, however, that doing so allows modern scientists to distinguish their “objective” study of biological racial difference from the ridiculous “pseudoscience” of the past. Professor Roberts observes that “what we call racial pseudoscience today was considered the vanguard of scientific progress at the time it was practiced.” (27-28). In other words, we must be careful to briskly dismiss the “racial science” of the 19th Century as pseudoscience, lest we fall into the trap (comforting to some) of believing that current genetic examinations of racial difference are somehow distinctly free from unsound empirical assumptions and implicit bias. As Professor Roberts argues, “[t]he burning scientific questions of each period have been framed and answered in terms of race not because rational scientific inquiry compelled it, but because race was presumed to be an essential biological category.” (28)…

Read the entire review here.

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