Mixed Race Studies

The Mulatto a Hybrid-probable extermination of the two races if the Whites and Blacks are allowed to intermarry

The American Journal of the Medical Sciences
Volume 6, Issue 11 (July 1843)
pages 252-256

Josiah C. Nott, M.D.
Mobile, Alabama

The reader will probably be astonished at this late clay to sec so novel an assertion us that the mulatto is a hybrid; but I hope ho will read and ponder upon the diets given below before be concludes that it has no foundation in reason.

A writer in the Boston Medical and Surgical Journal, under the signature of ” Philanthropist,” has made the following important and interesting statements:—

• “From authentic statistics and extensive corroborating information, obtained from sources, to me of unquestionable authority, together with my own observation, I am led to believe that the following statements are substantially correct.
• 1st, ” That the longevity of the pure Africans is greater than that of the inhabitants of any other part of the globe.”
• 2d, “That the mulattoes, i. e. those born of parents one being African and the other Caucasian or white, are decidedly the shortest lived of any class of the human race.”
• 3d, “That the mulattoes are no more liable to die under the age of 25* than the whites or blacks; but from 85 to 40, their deaths are as 10 to 1 of either the whites or blacks between those ages—from 40 to 55, 50 to 1–and from 55 to 70, 100 to 1.”
• 4th, “That the mortality of the free people of colour in the United States, is more than 100 per cent, greater than that of the slaves.”
• 5th, “That those of unmixed African extraction in the “free states” are not more liable to sickness or premature death than the whiles of their rank and condition in society; but that the striking mortality, so manifest amongst the free people of colour, is in every community and section of the country, invariably confined to the mulattoes.”

The following extracts are from the same writer:—

“It was remarked by a gentleman eminent for his intellectual attainments and distinguished for his correct observation, and who had lived many years in the Southern States, that he did not believe be had ever seen a mulatto 70 years of age.”…

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Race and global patterns of phenotypic variation

American Journal of Physical Anthropology
Volume 139, Issue 1 (May 2009) Special Issue: Race Reconciled: How Biological Anthropologists View Human Variation
pages 16–22
DOI: 10.1002/ajpa.20900

John H. Relethford, Distinguished Teaching Professor of Anthropology
State University of New York, Oneonta

Phenotypic traits have been used for centuries for the purpose of racial classification. Developments in quantitative population genetics have allowed global comparison of patterns of phenotypic variation with patterns of variation in classical genetic markers and DNA markers. Human skin color shows a high degree of variation among geographic regions, typical of traits that show extensive natural selection. Even given this high level of geographic differentiation, skin color variation is clinal and is not well described by discrete racial categories. Craniometric traits show a level of among-region differentiation comparable to genetic markers, with high levels of variation within populations as well as a correlation between phenotypic and geographic distance. Craniometric variation is geographically structured, allowing high levels of classification accuracy when comparing crania from different parts of the world. Nonetheless, the boundaries in global variation are not abrupt and do not fit a strict view of the race concept; the number of races and the cutoffs used to define them are arbitrary. The race concept is at best a crude first-order approximation to the geographically structured phenotypic variation in the human species.

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Racial Classification Regarding Semen Donor Selection in Brazil

Developing World Bioethics
Volume 7, Issue 2 (August 2007)
pages 104–111
DOI: 10.1111/j.1471-8847.2007.00192.x

Rosely Gomes Costa, Pós-doutorado em Ciências Sociais pela
Universidade Estadual de Campinas (UNICAMP) e pela Universidade Autônoma de Barcelona (Espanha)

Brazil has not yet approved legislation on assisted reproduction. For this reason, clinics, hospitals and semen banks active in the area follow Resolution 1358/92 of the Conselho Federal de Medicina, dated 30 September 1992. In respect to semen donation, the object of this article, the Resolution sets out that gamete donation shall be anonymous, that is, that the donor and recipients (and the children who might subsequently be born) shall not be informed of each other’s identity. Thus, since recipients are unaware of the donor’s identity, semen banks and the medical teams involved in assisted reproduction become the intermediaries in the process. The objective of this article is to show that, in practice, this represents disrespect for the ethical principles of autonomy, privacy and equality. The article also stresses that the problem is compounded by the racial question. In a country like Brazil, where racial classification is so flexible and goes side by side with racist attitudes, the intermediary role played by semen banks and medical teams is conditioned by their own criteria of racial classification, which are not always the same as those of donors and semen recipients. The data presented in this paper were taken from two semen banks located in the city of São Paulo (Brazil). At the time of my research, they were the only semen banks in the state of São Paulo and supplied semen to the capital (São Paulo city), the state of São Paulo, and to cities in other Brazilian states where semen banks were not available.

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Interethnic diversity of NAT2 polymorphisms in Brazilian admixed populations

BMC Genetics
Volume 11, Number 1 (2010-10-05)
pages 87-93
DOI: 10.1186/1471-2156-11-87

Jhimmy Talbot
Laboratório de Farmacogenômica e Epidemiologia Molecular
Universidade Estadual de Santa Cruz

Luiz Alexandre V. Magno
Laboratório de Farmacogenômica e Epidemiologia Molecular
Universidade Estadual de Santa Cruz

Cinthia VN Santana
Laboratório de Farmacogenômica e Epidemiologia Molecular
Universidade Estadual de Santa Cruz

Sandra MB Sousa
Laboratório de Farmacogenômica e Epidemiologia Molecular
Universidade Estadual de Santa Cruz

Paulo RS Melo
Laboratório de Farmacogenômica e Epidemiologia Molecular
Universidade Estadual de Santa Cruz

Ronan X. Correa
Laboratório de Farmacogenômica e Epidemiologia Molecular
Universidade Estadual de Santa Cruz

Giuliano Di Pietro
Laboratório de Farmacogenômica e Epidemiologia Molecular
Universidade Estadual de Santa Cruz

Fabrício Rios-Santos
Laboratório de Farmacogenômica e Epidemiologia Molecular
Universidade Estadual de Santa Cruz

Background

N-acetyltransferase type 2 (Nat2) is a phase II drug- metabolizing enzyme that plays a key role in the bioactivation of aromatic and heterocyclic amines. Its relevance in drug metabolism and disease susceptibility remains a central theme for pharmacogenetic research, mainly because of its genetic variability among human populations. In fact, the evolutionary and ethnic-specific SNPs on the NAT2 gene remain a focus for the potential discoveries in personalized drug therapy and genetic markers of diseases. Despite the wide characterization of NAT2 SNPs frequency in established ethnic groups, little data are available for highly admixed populations. In this context, five common NAT2 SNPs (G191A, C481T, G590A, A803G and G857A) were investigated in a highly admixed population comprised of Afro-Brazilians, Whites, and Amerindians in northeastern Brazil. Thus, we sought to determine whether the distribution of NAT2 polymorphism is different among these three ethnic groups.

Results

Overall, there were no statistically significant differences in the distribution of NAT2 polymorphism when Afro-Brazilian and White groups were compared. Even the allele frequency of 191A, relatively common in African descendents, was not different between the Afro-Brazilian and White groups. However, allele and genotype frequencies of G590A were significantly higher in the Amerindian group than either in the Afro-Brazilian or White groups. Interestingly, a haplotype block between G590A and A803G was verified exclusively among Amerindians.

Conclusions

Our results indicate that ethnic admixture might contribute to a particular pattern of genetic diversity in the NAT2 gene and also offer new insights for the investigation of possible new NAT2 gene-environment effects in admixed populations.

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Ancestry DNA and the Manipulation of Afro-Indian Identity

Chapter in:
The First and the Forced: Essays on the Native American and African American Experience
2007
285 pages
University of Kansas, Hall Center for the Humanities

Edited by James N. Leiker, Kim Warren, and Barbara Watkins

Chapter pages: pages 141-155

Arica L. Coleman, Assistant Professor of Black American Studies
Unverisity of Delaware

Arica Coleman explains the rise in popularity of Ancestry DNA testing to determine more clearly an ancestral past for African Americans and Native Americans. In this essay, she shows that claims made by commercial companies promising to provide missing evidence for African and indigenous origins are more exaggerated than current genetic technology can deliver. Promises that a DNA test can provide a verification of Native American tribal relationships or define a link to an African tribe are misleading. Coleman argues that Ancestry DNA results are largely based on speculation and can vary from one company to the next. She also asserts that in developing identities, a shared history and ancestral consciousness, including knowledge transmitted through oral history, culture, and daily activities, should not be replaced by genetic technologies.

Read the entire chapter here.

Post-Racial? Americans and Race in the Age of Obama

The Greenlining Institute
Berkeley, California
November 2011
26 pages

Dr. Daniel Byrd, Research Director

Bruce Mirken, Media Relations Coordinator

Since the election of Barack Obama as the United States’ first African American president, there has been much discussion of whether this means the U.S. has become a “post-racial” society. Does race still matter in America? This question is particularly significant in light of the fact that within about three decades, people of color are projected to become the majority. Policy based on mistaken assumptions could cripple efforts to revive the U.S. economy. Using the most definitive survey data available, we investigated perceptions of race in America among different racial and ethnic groups and how those perceptions compare to measurable realities of U.S. society.

Table of Contents

• Executive Summary
• Recommendations
• Introduction
  • Methodology
  • America’s Changing Demographics
  • Race Relations in America
  • Perceptions of Discrimination and Inequality in America
  • Race and Health
  • Race and Income
  • Race and Treatment of Groups by the Federal Government
  • Results
  • Discussion
  • Summary
  • A Call to Action
• References
• Appendix I
• Appendix II

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Panel to discuss racism and medical issues

The Daily Bruin
University of California, Los Angeles
2012-02-10

Ariana Ricarte

The topic of racism in health care, genetics and other medical issues will be the central point of discussion at a panel in De Neve Auditorium on Saturday [13:00-15:00 PST].

The panel, called “Race in Medicine: A Dangerous Prescription,” will discuss disparities between people of different races in the health care system and the ways a patient’s ethnicity can affect decisions made by doctors and insurance companies. The event is hosted by UCLA’s Mixed Student Union, a student group founded in 2010 that aims to provide a safe and open environment for people of multiracial and multiethnic heritage, said chairwoman Camila Lacques.

The panel will go over topics such as the role of ethnicity in prescription medicine and bone marrow and stem cell transplants. When it comes to transplants, multiracial people have a more difficult time finding matches because of their unique genetic composition, said panelist Athena Asklipiadis…

[Note by Steven F. Riley: Everyone—except their identical twin—has an “unique genetic composition.”  Race is a social, not biological construction and as such, is not linked to genetics. Please read Dorothy Roberts excellent (and sobering) monograph on race and medicine titled, Fatal Invention: How Science, Politics, and Big Business Re-create Race in the Twenty-First Century for more information.]

…G. Reginald Daniel, a panelist at Saturday’s event and a sociology professor at UC Santa Barbara, said he plans to focus on the positive and negative images applied to multiracial people, as well as talk about the issue in terms of genetic variety.

“I think people need to step out of mono-racial thinking,” Daniel said. “We need to see the connections we have with each other, whether we like it or not.”…

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Use of Blood Groups in Human Classification

Science Magazine
Volume 112, Number 2903 (1950-08-18)
pages 187-196
DOI: 10.1126/science.112.2903.187

William C. Boyd
Boston University School of Medicine, Boston, Massachusetts

—Will he not fancy that the shadows which he formerly saw are truer than the objects which are now shown to him!
Plato, The Republic

In recent years there has been an increasing feeling, on the part of both geneticists and physical anthropologists, that genetical methods ought to be applied to the problems of the classification of man, and a number of proposals to this effect have been made. Nevertheless, new books of anthropology, as they have been published, have been found to contain much the same old classifications based on morphological characteristics, skin color, etc., even though the authors may have started with the announced intention of making use of the newer methods. It is clear that many a worker, attempting to apply genetical methods of taxonomy to man, has been disappointed, and, in fact, one scientist, formerly quite active in the field of physical anthropology, has now given it up, and announced in a letter to me: “I tried to see what blood groups would tell me about ancient man, and found the results very disappointing.”

A careful analysis of the situation will show that such disappointment is based largely on two circumstances. First, there is the fact that the blood grouping genes affect invisible serological characteristics of the individual, and are thus never visible to the naked eye. It is to be feared that we are all too much inclined to be impressed by the visible as opposed to the invisible. Second, there is the fact that the layman’s concept of race (which is that the human species can be divided up by valid, scientific methods, into various groups that are pretty different from each other and which will look pretty different from each other) has been unconsciously retained by many scientific workers, and the hypothetical dissenting readers are unconsciously expecting that the new system we propose to introduce will also provide us with startling differences in the appearance and behavior of the different “races” we define, and will feel let down to discover that the new classification does not, when all is said about it, reveal any very dramatic results.

If the blood grouping genes had affected, not characteristics of the blood, but prominent morphological or physical characteristics such as the shape of the head, color of the skin, etc., there cannot be the slightest question that they would already have been made the chief basis of a racial classification and would have been considered entirely adequate for that purpose.

Equivalence of Genes

From our knowledge of genetics we may see that there is nothing fundamentally different between the blood grouping genes as genes, and the genes which do affect morphological features. It is simply a historical accident that fairly adequate information was obtained about the mode of transmission of blood grouping genes before any information at all equivalent in amount or value was obtained about the genes affecting physical appearance.

In view of these facts, and since there seems to be no reason to suppose that the location of a gene in a chromosome, or the nature of the particular chromosome in which the gene resides, determines in advance the main or even the subsidiary characteristics which are to be influenced by the gene, it might be instructive to let our imaginations roam a bit. The outwardly observable effects of the blood group genes are, so far as we know, zero. Therefore let us make some arbitrary assumptions as to the sort of effect which the blood grouping genes could have produced, supposing them to have affected some of the external and visible char-…

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Race mixture: a social or a biological problem?

The Eugenics Review
Volume 41, Number 2 (July 1949)
pages 81-85

A. Dickinson

The ideas of the layman on race are curiously distorted. Race is commonly identified with a given language or culture, with a group living in a common habitat or possessing a single characteristic feature such as pigmentation. Men stubbornly cling to concepts of racial purity and elaborate these into theories of racial superiority or inferiority. Needless to say, this human weakness is often attended by dire results in a world in which people of differing physical traits are being herded ever more closely together as the barriers of distance are gradually broken down…

…Prevalence of Hybridization

Yet objective investigation on scientific lines clearly shows that only the broadest classification is possible in respect of physical traits, a classification which reduces the teeming millions of the world, and the multitude of self-styled races into which they divide themselves, into perhaps no more than five main groups. Likewise empirical proof has been given that intra-racial variability often exceeds inter-racial variability in respect of measurable physical traits…

…We speak in general terms. It is impossible to do more by way of an introduction to a study of race mixture, but it is clear from the foregoing generalizations that concepts of racial purity are largely invalid and that the psychic homogeneity of the human species is much greater than is commonly supposed. It is also evident that differences in language and culture are by no means coincident with differences in physical traits. A rational approach to the question is needed-one which dispenses with what can only be the dead-weight of national ideologies and which acknowledges that an excessive degree af miscegenation must have taken place over thousands of years to account for the present day distribution of physical traits and the variability about a norm which obtains in even the most race-conscious of societies. Given the psychological abhorrence of race mixture which persists as a corollary of untenable theories of racial purity, we must endeavour to assess in quantitative and qualitative terms the indisputable fact of race mixture as it exists in the world to-day…

…Social Aspects of Hybridization

This of course throws into high relief the psychological and social aspects of the question. A strong psychological prejudice against race mixture will inevitably result in the concept of hybrid inferiority. This in turn will often prevent hybrids from revealing their true potentialities. Widely regarded as social outcasts they will find it well-nigh impossible to rise to the position in society which might well be their due. As a consequence their minds will become warped and their personalities stunted. It is not surprising that hybrids, particularly those living alongside their progenitors, commonly reveal a minimum of ability, marked indolence and an astonishing proclivity towards moral laxity. Yet the condition of such people can hardly be attributed to biological factors. Rather is it due to their lack of opportunity in a society which is at once prejudiced and highly irrational in outlook. In the words of Young, ” the social behaviour of hybrids is best considered as a reflection of their cultural milieu than as resulting from biological sources.” Castle, too, makes the same point by contrasting the crossbreeding of black and white and red and white in the United States. The blacks and the mulattoes are visited with strong social disapprobation, their opportunities for advancement are limited, their numbers decrease and, if the mulatto compares favourably with his black progenitors, it is only because in the past the whites, his blood relations, have shown at least a modicum of compassion for their unfortunate offspring, whereas the lot of the pure-blooded Negro has always been an unfortunate one in the land of his enslavement. That the mulattoes will not stand comparison with the whites goes without saying. But their plight should be contrasted with that of the Indian hybrids in whose case there is no strong social prejudice. It should be borne in mind how well they thrive, how they are assimilated back into the white population, how they frequently attain positions of considerable authority and responsibility to which they are fully equal. Here the difference in the results between the aforementioned crossings are not referable to any biological harmony or disharmony, but wholly to the social attitude adopted by the whites, favourable in one case, unfavourable in the other…

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With DNA Testing, Suddenly They Are Family

The New York Times
2011-01-24

Rachel L. Swarns

ST. LOUIS — Growing up, Khrys Vaughan always believed that she had inherited her looks and mannerisms from her father, and that her appreciation for tradition and old-fashioned gentility stemmed from her parents’ Southern roots. But those facets of her self-image crumbled when she was told, at age 42, that she had been adopted.

She began searching for her origins, only to find out that her adoption records had been sealed, a common practice in the 1960s. Then Mrs. Vaughan stumbled across an ad from a DNA testing company offering to help people who had been adopted find clues to their ancestry and connections to blood relatives.

About five weeks after shipping off two tiny vials of her cells from a swab of her cheek, Mrs. Vaughan received an e-mail informing her that her bloodlines extended to France, Romania and West Africa. She was also given the names and e-mail addresses of a dozen distant cousins. This month, she drove 208 miles from her hometown here to Evansville, Ind., to meet her third cousin, the first relative to respond to her e-mails. Mrs. Vaughan is black and her cousin is white, and they have yet to find their common ancestor. But Mrs. Vaughan says that does not matter…

…Within minutes of receiving the names of her distant relatives, Mrs. Vaughan, a freelance project manager, was admiring their photographs on Facebook. Another adoptee who found family through DNA testing, Kathy Borgmann, a 49-year-old corn farmer in New Palestine, Ind., exchanged e-mails with cousins who delighted her by saying, “Welcome to the family.”…

…Not everyone is hoping to find new relatives. Some adoptees who have found genetic matches have been rebuffed by their distant kin. Most people take genealogical DNA tests to fill gaps in their family trees, not to find new members of their clans. Mr. Bogner said several cousins identified through DNA testing stopped communicating once they learned he was adopted. “It was horribly disappointing,” he said…

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